You can use 1 cup of butter in place of crisco, or 1 cup of margarine + subtract 1/2 teaspoon of the called for salt in the recipe.

Lard is also a good replacement for crisco.

For baking you could also use prunes, applesauce, apple butter for up to 3/4 of the crisco in a recipe.

Use olive oil, vegetable oil, beer or wine (for sauteing) for frying or sauteing. Or you could also use clarified butter also called drawn butter and I think it the same thing as ghee.

Hope these suggestions are helpful!